Asian online Y-STR Haplotype Reference Database.

نویسندگان

  • Ruediger Lessig
  • Sascha Willuweit
  • Michael Krawczak
  • Fang-Chin Wu
  • Chang-En Pu
  • Wook Kim
  • Lotte Henke
  • Juergen Henke
  • Jasmin Miranda
  • Monika Hidding
  • Mark Benecke
  • Cornelia Schmitt
  • Michelle Magno
  • Gayvelline Calacal
  • Frederick C Delfin
  • Maria Corazon A de Ungria
  • Sahar Elias
  • Christa Augustin
  • Zaw Tun
  • Katsuja Honda
  • Manfred Kayser
  • Leonor Gusmao
  • António Amorim
  • Cintia Alves
  • Yiping Hou
  • Christine Keyser
  • Bertrand Ludes
  • Michael Klintschar
  • Uta D Immel
  • Barbara Reichenpfader
  • Boriana Zaharova
  • Lutz Roewer
چکیده

For several years Y-chromosomal microsatellites (short tandem repeats, STRs) have been well established in forensic practice. In this context, the genetic characteristics of the Y chromosome (i.e. its paternal inheritance and lack of recombination) render STRs particularly powerful. However, genetic differences between male populations appear to be larger for Y-STRs than for autosomal STRs, a fact that is most likely due to the higher sensitivity of Y-chromosomal lineages to genetic drift (Forensic Sci Int 118 (2001) 153). The assessment of probabilities for matches between haplotyped male persons or traces/persons requires the typing of a large number of haplotypes in the appropriate reference populations. The haplotype data of a large number of European as well as South and North American populations have been collected and are continuously published online (Y-STR Haplotype Reference Database--YHRD; http://www.ystr.org). The most recent multicentric effort has led to the establishment of an Asian YHRD (http://www.ystr.org/asia) which has been available since January 2002. All databases are maintained and curated at the Institute of Legal Medicine, Humboldt-University, Berlin and will soon be fused to a global repository including populations from all continents.

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عنوان ژورنال:
  • Legal medicine

دوره 5 Suppl 1  شماره 

صفحات  -

تاریخ انتشار 2003